{"id":187314,"date":"2022-09-28T07:14:51","date_gmt":"2022-09-28T14:14:51","guid":{"rendered":"https:\/\/lifesciences.csoftintl.com\/?p=187314"},"modified":"2022-09-29T20:40:59","modified_gmt":"2022-09-30T03:40:59","slug":"crispr-therapeutics%e5%ae%a3%e5%b8%83ctx130%e8%8e%b7%e5%be%97fda%e5%86%8d%e7%94%9f%e5%8c%bb%e5%ad%a6%e9%ab%98%e7%ba%a7%e7%96%97%e6%b3%95%e6%8c%87%e5%ae%9a","status":"publish","type":"post","link":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/blog\/crispr-therapeutics%e5%ae%a3%e5%b8%83ctx130%e8%8e%b7%e5%be%97fda%e5%86%8d%e7%94%9f%e5%8c%bb%e5%ad%a6%e9%ab%98%e7%ba%a7%e7%96%97%e6%b3%95%e6%8c%87%e5%ae%9a\/","title":{"rendered":"CRISPR Therapeutics\u5ba3\u5e03CTX130\u2122\u83b7\u5f97FDA\u518d\u751f\u533b\u5b66\u9ad8\u7ea7\u7597\u6cd5\uff08RMAT\uff09\u6307\u5b9a\uff0c\u7528\u4e8e\u6cbb\u7597\u76ae\u80a4T\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CTCL\uff09"},"content":{"rendered":"

CRISPR Therapeutics\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aCRSP\uff09\uff0c\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u4e3a\u91cd\u5927\u75be\u75c5\u521b\u9020\u53d8\u9769\u6027\u57fa\u56e0\u836f\u7269\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u5ba3\u5e03\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88CTX130\u2122\u518d\u751f\u533b\u5b66\u9ad8\u7ea7\u7597\u6cd5\uff08RMAT\uff09\u6307\u5b9a\uff0c\u8be5\u7597\u6cd5\u662f\u516c\u53f8\u5168\u8d44\u62e5\u6709\u7684\u9488\u5bf9CD70\u7684\u5f02\u4f53CAR T\u7ec6\u80de\u7597\u6cd5\uff0c\u7528\u4e8e\u6cbb\u7597\u771f\u83cc\u75c5\u548c\u585e\u8428\u91cc\u7efc\u5408\u75c7\uff08MF\/SS\uff09\u3002<\/p>\n

\u6839\u636e\u300a21\u4e16\u7eaa\u6cbb\u6108\u6cd5\u6848\u300b\u8bbe\u7acb\u7684RMAT\u6307\u5b9a\u65e8\u5728\u52a0\u5feb\u6709\u524d\u9014\u7684\u7ba1\u9053\u4ea7\u54c1\u7684\u836f\u7269\u5f00\u53d1\u548c\u5ba1\u67e5\u8fc7\u7a0b\uff0c\u5305\u62ec\u57fa\u56e0\u7597\u6cd5\u3002\u5982\u679c\u4e00\u79cd\u518d\u751f\u533b\u5b66\u7597\u6cd5\u65e8\u5728\u6cbb\u7597\u3001\u6539\u53d8\u3001\u9006\u8f6c\u6216\u6cbb\u6108\u4e00\u79cd\u4e25\u91cd\u7684\u6216\u5371\u53ca\u751f\u547d\u7684\u75be\u75c5\u6216\u75c5\u75c7\uff0c\u5e76\u4e14\u521d\u6b65\u4e34\u5e8a\u8bc1\u636e\u8868\u660e\u8be5\u836f\u7269\u6216\u7597\u6cd5\u6709\u53ef\u80fd\u89e3\u51b3\u8fd9\u79cd\u75be\u75c5\u6216\u75c5\u75c7\u7684\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff0c\u5219\u6709\u8d44\u683c\u83b7\u5f97RMAT\u6307\u5b9a\u3002\u4e0e\u7a81\u7834\u6027\u7597\u6cd5\u6307\u5b9a\u4e00\u6837\uff0cRMAT\u6307\u5b9a\u4f53\u73b0\u4e86FDA\u5173\u4e8e\u9ad8\u6548\u836f\u7269\u5f00\u53d1\u7684\u5bc6\u96c6\u6307\u5bfc\u7684\u597d\u5904\uff0c\u5305\u62ec\u4e0eFDA\u65e9\u671f\u4e92\u52a8\u8ba8\u8bba\u66ff\u4ee3\u6216\u4e2d\u95f4\u7ec8\u70b9\u7684\u80fd\u529b\uff0c\u652f\u6301\u52a0\u901f\u6279\u51c6\u548c\u6ee1\u8db3\u6279\u51c6\u540e\u8981\u6c42\u7684\u6f5c\u5728\u65b9\u6cd5\uff0c\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\u7684\u6f5c\u5728\u4f18\u5148\u5ba1\u67e5\u548c\u5176\u4ed6\u52a0\u5feb\u5f00\u53d1\u548c\u5ba1\u67e5\u7684\u673a\u4f1a\u3002<\/p>\n

\u4e86\u89e3\u66f4\u591a<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

CRISPR Therapeutics\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aCRSP\uff09\uff0c\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u4e3a\u91cd\u5927\u75be\u75c5\u521b\u9020\u53d8\u9769\u6027\u57fa\u56e0\u836f\u7269\u7684 […]<\/p>\n","protected":false},"author":3,"featured_media":184904,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false},"categories":[953,368,467,1305,1088,754],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/187314"}],"collection":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=187314"}],"version-history":[{"count":1,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/187314\/revisions"}],"predecessor-version":[{"id":187315,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/187314\/revisions\/187315"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/media\/184904"}],"wp:attachment":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=187314"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=187314"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=187314"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}