{"id":174548,"date":"2022-01-21T15:43:18","date_gmt":"2022-01-21T22:43:18","guid":{"rendered":"https:\/\/lifesciences.csoftintl.com\/?p=174548"},"modified":"2022-01-29T00:54:11","modified_gmt":"2022-01-29T07:54:11","slug":"ao-176%e7%9a%84%e8%8d%af%e7%89%a9%e6%8c%87%e5%ae%9a%ef%bc%9a%e6%b2%bb%e7%96%97%e5%a4%9a%e5%8f%91%e6%80%a7%e9%aa%a8%e9%ab%93%e7%98%a4","status":"publish","type":"post","link":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/blog\/ao-176%e7%9a%84%e8%8d%af%e7%89%a9%e6%8c%87%e5%ae%9a%ef%bc%9a%e6%b2%bb%e7%96%97%e5%a4%9a%e5%8f%91%e6%80%a7%e9%aa%a8%e9%ab%93%e7%98%a4\/","title":{"rendered":"AO-176\u7684\u836f\u7269\u6307\u5b9a\uff1a\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624"},"content":{"rendered":"<p>\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u7ecf\u6388\u4e88Arch Oncology\u516c\u53f8\u7684\u4e0b\u4e00\u4ee3\u6297CD47 IgG2\u6297\u4f53AO-176 &#8220;\u5b64\u513f\u836f &#8220;\u79f0\u53f7\uff08ODD\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08r\/r MM\uff09\u3002\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u662f\u4e00\u79cd\u9aa8\u9ad3\u4e2d\u6210\u719f\u6d46\u7ec6\u80de\u7684\u764c\u75c7\uff0c\u8be5\u75c5\u4e0e\u53d1\u751f\u5728\u808b\u9aa8\u3001\u80cc\u90e8\u548c\u9aa8\u76c6\u7684\u75c5\u53d8\u6709\u5173\uff0c\u5e76\u5bfc\u81f4\u4e25\u91cd\u75bc\u75db\u3002\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u4f1a\u8fdb\u4e00\u6b65\u524a\u5f31\u514d\u75ab\u7cfb\u7edf\uff0c\u589e\u52a0\u5bf9\u611f\u67d3\u548c\u9ad8\u9499\u8840\u75c7\u7684\u6613\u611f\u6027\u3002\u6297\u4f53\u6cbb\u7597\uff0cAO-176\uff0c\u963b\u65ad\u4fe1\u53f7\u8c03\u8282\u86cb\u767d\u03b1\uff08SIRP\u03b1\uff09\u548c\u8de8\u819c\u86cb\u767dCD47\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u6709\u6548\u5730\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u7684\u541e\u566c\u3002\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684\u5e38\u89c1\u6cbb\u7597\u65b9\u6848\u5305\u62ec\u653e\u7597\u3001\u5316\u7597\u3001\u9aa8\u9ad3\u79fb\u690d\u548c\u764c\u75c7\u7ec6\u80de\u9776\u5411\u7597\u6cd5\u3002Arch Oncology\u662f\u4e00\u5bb6\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u514d\u75ab\u80bf\u7624\u5b66\u516c\u53f8\uff0c\u4e3a\u5b9e\u4f53\u7624\u548c\u8840\u6db2\u5b66\u6076\u6027\u80bf\u7624\u60a3\u8005\u5f00\u53d1\u86cb\u767d\u8d28\u6700\u4f73\u7597\u6cd5\u3002<\/p>\n<p>\u9605\u8bfb<a href=\"https:\/\/www.biospace.com\/article\/releases\/arch-oncology-receives-u-s-fda-orphan-drug-designation-for-ao-176-a-next-generation-anti-cd47-igg2-antibody-for-the-treatment-of-multiple-myeloma\/?s=74\">\u66f4\u591a<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u7ecf\u6388\u4e88Arch Oncology\u516c\u53f8\u7684\u4e0b\u4e00\u4ee3\u6297CD47 IgG2\u6297\u4f53AO-17 [&hellip;]<\/p>\n","protected":false},"author":29,"featured_media":174454,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false},"categories":[953,467,754],"tags":[752,1394,1379,1454,1400,1499,1500],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/174548"}],"collection":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=174548"}],"version-history":[{"count":1,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/174548\/revisions"}],"predecessor-version":[{"id":174553,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/174548\/revisions\/174553"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/media\/174454"}],"wp:attachment":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=174548"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=174548"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=174548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}