{"id":174180,"date":"2022-01-04T14:41:23","date_gmt":"2022-01-04T21:41:23","guid":{"rendered":"https:\/\/lifesciences.csoftintl.com\/?p=174180"},"modified":"2022-01-18T00:52:56","modified_gmt":"2022-01-18T07:52:56","slug":"ind%e6%89%b9%e5%87%86%ef%bc%9acstone-pharma%e7%9a%84cs5001-adc%e7%9e%84%e5%87%86ror1","status":"publish","type":"post","link":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/blog\/ind%e6%89%b9%e5%87%86%ef%bc%9acstone-pharma%e7%9a%84cs5001-adc%e7%9e%84%e5%87%86ror1\/","title":{"rendered":"IND\u6279\u51c6\uff1aCStone Pharma\u7684CS5001 ADC\u7784\u51c6ROR1"},"content":{"rendered":"

Cstone\u5236\u836f\u516c\u53f8\u65e5\u524d\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5bf9CS5001\u53d1\u51fa\u4e86\u7814\u7a76\u8fdb\u5c55\uff08SMP\uff09\u51fd\uff0c\u5e76\u6279\u51c6\u4e86CS5001\u7684\u7814\u7a76\u6027\u65b0\u836f\uff08IND\uff09\u7533\u8bf7\uff0cCS5001\u662f\u4e00\u79cd\u6f5c\u5728\u7684\u6297\u4f53-\u836f\u7269\u7ed3\u5408\u7269\uff08ADC\uff09\uff0c\u9488\u5bf9\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6837\u5b64\u513f\u53d7\u4f531\uff08ROR1\uff09\u3002ROR1\u662f\u4e00\u79cd\u80ce\u513f\u86cb\u767d\uff0c\u5728\u6210\u4eba\u7ec4\u7ec7\u4e2d\u4f4e\u8868\u8fbe\u6216\u4e0d\u8868\u8fbe\uff0c\u4f46\u5728\u4e00\u4e9b\u764c\u75c7\u4e2d\u9ad8\u8868\u8fbe\uff0c\u5305\u62ec\u767d\u8840\u75c5\u3001\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u3001\u4e73\u817a\u764c\u3001\u80ba\u764c\u548c\u5375\u5de2\u764c\uff0c\u4f7f\u5176\u6210\u4e3aADC\u7684\u7406\u60f3\u76ee\u6807\u3002CS5001\u662f\u4e00\u79cd\u4e34\u5e8a\u9636\u6bb5\u7684ADC\uff0c\u5b83\u5229\u7528\u591a\u79cd\u5dee\u5f02\u5316\u7279\u5f81\u7784\u51c6ROR1\uff0c\u5305\u62ec\u4e13\u6709\u7684\u4f4d\u70b9\u7279\u5f02\u6027\u7ed3\u5408\u3001\u80bf\u7624\u9009\u62e9\u6027\u53ef\u88c2\u89e3\u8fde\u63a5\u7269\u548c\u5421\u54af\u5e76\u4e8c\u6c2e\u6742\u5353\uff08PBD\uff09\u539f\u836f\u6280\u672f\u3002\u5230\u8fbe\u80bf\u7624\u540e\uff0c\u8fde\u63a5\u5242\u548c\u539f\u836f\u88ab\u88c2\u89e3\uff0c\u91ca\u653e\u51faPBD\u6bd2\u7d20\uff0c\u5728\u764c\u7ec6\u80de\u5185\u4ea7\u751f\u81f4\u547d\u7684DNA\u4ea4\u8054\u3002CStone Pharmaceuticals\u662f\u4e00\u5bb6\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u514d\u75ab\u80bf\u7624\u7597\u6cd5\u548c\u7cbe\u51c6\u836f\u7269\u7684\u7814\u7a76\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

Cstone\u5236\u836f\u516c\u53f8\u65e5\u524d\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5bf9CS5001\u53d1\u51fa\u4e86\u7814\u7a76\u8fdb\u5c55\uff08SMP\uff09\u51fd\uff0c\u5e76\u6279\u51c6\u4e86 […]<\/p>\n","protected":false},"author":29,"featured_media":173938,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false},"categories":[953,467,781,754],"tags":[752,1455,1456,1379,1454,1374,1400],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/174180"}],"collection":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=174180"}],"version-history":[{"count":0,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/posts\/174180\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/media\/173938"}],"wp:attachment":[{"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=174180"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=174180"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifesciences.csoftintl.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=174180"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}